A retrospective study of infection after onlay graft / 中华口腔医学杂志

<p><b>OBJECTIVE</b>To investigate the treatment and prevention of infection after alveolar crest onlay bone graft.</p><p><b>METHODS</b>From January 2006 to May 2010, 11 infection cases after onlay graft on alveolar crest were reviewed to evaluate the infection time, clinical situation, treatment measure, and therapeutic effect.</p><p><b>RESULTS</b>The infection of all 11 cases occurred about 15 days after bone graft, which showed either soft tissue fistulae or bone graft exposure in the oral cavity. Three cases failed because of persistent infection. The infection of the other 8 cases was controlled after a series of comprehensive therapy, and most of the bone graft was reserved and implant restoration finally completed.</p><p><b>CONCLUSIONS</b>After the effective and comprehensive therapy, infected bone graft can be reserved. But to ensure the survival rate of bone graft, the most important thing is to prevent infection in perioperative period.</p>

Removal of nitrogen, phosphorus, and organic pollutants from water using seeding type immobilized microorganisms / 生物医学与环境科学（英文）

<p><b>OBJECTIVE</b>To study the possibility of removing nitrogen, phosphorus, and organic pollutants using seeding type immobilized microorganisms.</p><p><b>METHODS</b>Lakes P and M in Wuhan were chosen as the objects to study the removal of nitrogen, phosphorus, and organic pollutants with the seeding type immobilized microorganisms. Correlations between the quantity of heterotrophic bacteria and the total nitrogen (TN), total phosphorus (TP), and total organic carbon (TOC) in the two lakes were studied. The dominant bacteria were detected, inoculated to the sludge and acclimated by increasing nitrogen, phosphorus and decreasing carbon source in an intermittent, time-controlled and fixed-quantity way. The bacteria were then used to prepare the seeding type immobilized microorganisms, selecting diatomite as the adsorbent carrier. The ability and influence factors of removing nitrogen, phosphorus, and organic pollutant from water samples by the seeding type immobilized microorganisms were studied.</p><p><b>RESULTS</b>The coefficients of the heterotrophic bacterial quantity correlated with TOC, TP, and TN were 0.9143, 0.8229, 0.7954 in Lake P and 0.9168, 0.7187, 0.6022 in Lake M. Ten strains of dominant heterotrophic bacteria belonging to Pseudomonas, Coccus, Aeromonas, Bacillus, and Enterobateriaceae, separately, were isolated. The appropriate conditions for the seeding type immobilized microorgansims in purifying the water sample were exposure time=24 h, pH=7.0-8.0, and quantity of the immobilized microorganisms=0.75-1 g/50 mL. The removal rates of TOC, TP, and TN under the above conditions were 80.2%, 81.6%, and 86.8%, respectively.</p><p><b>CONCLUSION</b>The amount of heterotrophic bacteria in the two lakes was correlated with TOC, TP, and TN. These bacteria could be acclimatized and prepared for the immobilized microorganisms which could effectively remove nitrogen, phosphorus, and mixed organic pollutants in the water sample.</p>

Finite element analysis of the effects of implant thread locations on stress distribution / 华西口腔医学杂志

<p><b>OBJECTIVE</b>To investigate the effects of different implant thread locations on stress distribution in implant and bone under concentrated load, and discuss the best design of location of implant thread.</p><p><b>METHODS</b>The stress in implant-bone interface of implants with different thread locations (model A, B, C, D), which were loaded in axial and oblique 450 to axle, were analyzed by Solidworks 2005 plus and Cosmos/works 7.0 software.</p><p><b>RESULTS</b>The stresses in cervical cortical bone of implant with model C were lower than others. But under oblique load, the stresses of implant and cancellous bone in model C were higher than model A. The stresses distribution of model B was obviously concentrated, and under axial load, all kinds of stresses in this model were higher than others. The stress distribution in model A and D were more even, the stress concentrated more on implant neck, upper part of cortical bone and the lowest thread on implant. The stresses in interface under oblique load were much higher than those under axial load.</p><p><b>CONCLUSION</b>The location of thread has effect on stress distribution in implant-bone interface. More attention should be paid to it when we design implants, and we should try to avoid oblique load in implant prosthodontics.</p>

Mechanism of alopecia in patients with paraneoplastic pemphigus / 中国医学科学院学报

<p><b>OBJECTIVE</b>To investigate the relationship between the levels of antidesmoglein (DSG) 1, 3 antibodies in the sera of patients with paraneoplastic pemphigus (PNP) and alopecia.</p><p><b>METHODS</b>Sera from PNP patients, bullous pemphigoid patients, and normal healthy subjects were collected and 2 tissue samples from 2 healthy scalps were resected. Anti-DSG 1, 3 antibodies in the sera of PNP patients were detected by enzyme-linked immunosorbent assay (ELISA). Indirect immunofluorescent assay was used to detect whether the antibodies in the sera of PNP patients binds with the follicular epithelium of normal healthy scalp.</p><p><b>RESULTS</b>Anti-DSG3 autoantibody was strongly positive and anti-DSG1 weakly positive in one patient, while both two antibodies were negative in the other patient. Their sera could bind to keratinocytes and follicular epithelium in human scalp. Immunofluorescent signals were found on the intercellular epidermal cell surface and outer root sheath of the follicular epithelium. However, the immunofluorescent signals in the section incubating with serum of bullous pemphigoid were only found on basal membrane zone. No signals were found in the section incubating with normal healthy serum.</p><p><b>CONCLUSION</b>Alopecia in PNP patients are correlated with the anti-DSG3.</p>